Long before they develop neurofibrillary tangles or beta-amyloid plaques, brains with Alzheimer’s disease begin experiencing problems in their cells’ power plants — the mitochondria — that hinder their ability to make energy for cells.

Declines in gene expression related to mitochondria can occur in subjects as young as their early 30s.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
Arizona Researchers Say Genetic Changes Could Help Spot Alzheimer’s Disease Early