Researchers have found a new link between a cell’s basic life functions and its genetic operations. The connection involves a protein complex named SESAME, which uses enzymes responsible for glycolysis to activate proteins that regulate genetic material. Glycolysis is the first stage of cellular metabolism, the chain of biochemical reactions by which cells break down food, build proteins and amino acids, and produce energy.
Although their research involved yeast, the authors say the link may hold true in humans. If a SESAME equivalent in humans is found, it could offer insight to enable novel approaches for cancer risk prediction and treatment. Read my full press release at Stowers Institute for Medical Research:
Sacharomyces cerevisiae cells. Image courtesy Wikipedia Photo/Masur.
Researchers from the Stowers Institute for Medical Research and the University of Colorado Boulder have combined two optical systems to get around the natural limits of optical microscopes, which usually cannot see objects smaller than the wavelengths of light. Using this method, the team found that spindle pole bodies in yeast — tiny, tube-shaped structures essential to cell division — duplicate and form some structures at different times than once thought.
(This is one of a series of press releases I am writing for Stowers. They are a bit more technical than my usual articles, but each includes a more widely accessible summary at the end. I hope you’ll check them out!)
