Citizen Scientists Lose Sleep Over Black-Footed Ferrets Project

Wildlife specialist Jennifer Cordova holds a human trap containing the black-footed ferret captured by my group. Photo by Nicholas Gerbis.

For 11 years, volunteer citizen scientists have gathered near Seligman, Arizona, to help spot, capture and release endangered black-footed ferrets. The outing is part of a program to monitor captive-bred ferrets that wildlife specialists began reintroducing to Aubrey Valley 20 years ago.

This year, I joined them.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
Citizen Scientists Make Arizona Game And Fish Black-Footed Ferrets Project Possible

Jeopardy-Winning Computer Crunches Numbers to Fight ALS

Watson on Jeopardy stage set at the Computer History Museum in Mountain View, California. Photo by Atomic Taco.

Barrow Neurological Institute is working with IBM’s Jeopardy-winning supercomputer, Watson, to identify treatment targets for Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis, or ALS.

ALS is a poorly understood neuromuscular disease with only limited treatment options. Its capacity to strike anyone, at any time, seemingly without pattern, has puzzled researchers.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
BM’s Watson Computer Helps Barrow Identify New ALS Genes

TGen Brain Cancer Study Links Complexity to Treatability

TGen Headquarters. Photo by BenjaMurph.

New findings by the Translational Genomics Research Institute, or TGen, point to a surprising pattern in the brain cancer glioblastoma multiforme (GBM), the most common and deadly type of gliomas.

GBMs are aggressive, invasive and so genetically and structurally complex that advanced, targeted therapies have struggled to find vulnerabilities to attack.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
TGen Brain Cancer Study Finds Surprising Benefit In Tumor Complexity

Mitochondria-Linked Genetic Changes Might Give Early Hint of Alzheimer’s Disease

Diagram of a mitochondrion, courtesy of Arizona State University.

Long before they develop neurofibrillary tangles or beta-amyloid plaques, brains with Alzheimer’s disease begin experiencing problems in their cells’ power plants — the mitochondria — that hinder their ability to make energy for cells.

Declines in gene expression related to mitochondria can occur in subjects as young as their early 30s.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
Arizona Researchers Say Genetic Changes Could Help Spot Alzheimer’s Disease Early

Drug Targets Offer Hope for Less Painful, More Survivable Pancreatic Cancer

Image courtesy Centers for Disease Control and Prevention.
Image courtesy Centers for Disease Control and Prevention.

Scientists have identified drug targets that could one day make pancreatic cancer less painful — and more survivable — by knocking out key molecular signals. The signals form an essential part of the process by which cancer cells invade and spread through nearby nerves, wounding nerve endings.

Read/listen to my full story at KJZZ’s Arizona Science Desk:

New Drug Targets Could Reduce Pancreatic Cancer Pain, Improve Outcomes

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