Category Archives: Health

For Pancreatic Cancer, Biomarker Test Offers Chance for Early Detection

When cancer is detected,  the interaction of two nanoparticles creates a bright yellow signal (photo by Fei Lu, Houston Methodist Research Institute).

Pancreatic cancer is the fourth leading cause of cancer deaths in the United States each year, in part because around four-fifths of cases go undetected until they have reached an advanced stage. But a new, biomarker-based test could soon change all that — and offer a way to monitor treatment outcomes.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
Biomarker Test Offers Hope For Early Detection Of Pancreatic Cancer

Native Americans See Major Drop in Diabetes-Related Kidney Failure

Graph courtesy CDC.

The Centers for Disease Control and Prevention (CDC) reports that rates of diabetes-related kidney failure among Native Americans dropped more than 54 percent between 1996 and 2013.

The finding were published by CDC and the Special Diabetes Program for Indians (SDPI), a $150 million annual grant program coordinated by the Indian Health Service.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
Diabetes-Related Kidney Failure Among Native Americans Down 54 Percent

Jeopardy-Winning Computer Crunches Numbers to Fight ALS

Watson on Jeopardy stage set at the Computer History Museum in Mountain View, California. Photo by Atomic Taco.

Barrow Neurological Institute is working with IBM’s Jeopardy-winning supercomputer, Watson, to identify treatment targets for Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis, or ALS.

ALS is a poorly understood neuromuscular disease with only limited treatment options. Its capacity to strike anyone, at any time, seemingly without pattern, has puzzled researchers.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
BM’s Watson Computer Helps Barrow Identify New ALS Genes

TGen Brain Cancer Study Links Complexity to Treatability

TGen Headquarters. Photo by BenjaMurph.

New findings by the Translational Genomics Research Institute, or TGen, point to a surprising pattern in the brain cancer glioblastoma multiforme (GBM), the most common and deadly type of gliomas.

GBMs are aggressive, invasive and so genetically and structurally complex that advanced, targeted therapies have struggled to find vulnerabilities to attack.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
TGen Brain Cancer Study Finds Surprising Benefit In Tumor Complexity

Mitochondria-Linked Genetic Changes Might Give Early Hint of Alzheimer’s Disease

Diagram of a mitochondrion, courtesy of Arizona State University.

Long before they develop neurofibrillary tangles or beta-amyloid plaques, brains with Alzheimer’s disease begin experiencing problems in their cells’ power plants — the mitochondria — that hinder their ability to make energy for cells.

Declines in gene expression related to mitochondria can occur in subjects as young as their early 30s.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
Arizona Researchers Say Genetic Changes Could Help Spot Alzheimer’s Disease Early