Watson on Jeopardy stage set at the Computer History Museum in Mountain View, California. Photo by Atomic Taco.
Barrow Neurological Institute is working with IBM’s Jeopardy-winning supercomputer, Watson, to identify treatment targets for Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis, or ALS.
ALS is a poorly understood neuromuscular disease with only limited treatment options. Its capacity to strike anyone, at any time, seemingly without pattern, has puzzled researchers.
New findings by the Translational Genomics Research Institute, or TGen, point to a surprising pattern in the brain cancer glioblastoma multiforme (GBM), the most common and deadly type of gliomas.
GBMs are aggressive, invasive and so genetically and structurally complex that advanced, targeted therapies have struggled to find vulnerabilities to attack.
Diagram of a mitochondrion, courtesy of Arizona State University.
Long before they develop neurofibrillary tangles or beta-amyloid plaques, brains with Alzheimer’s disease begin experiencing problems in their cells’ power plants — the mitochondria — that hinder their ability to make energy for cells.
Declines in gene expression related to mitochondria can occur in subjects as young as their early 30s.
Image courtesy Centers for Disease Control and Prevention.
Scientists have identified drug targets that could one day make pancreatic cancer less painful — and more survivable — by knocking out key molecular signals. The signals form an essential part of the process by which cancer cells invade and spread through nearby nerves, wounding nerve endings.
Read/listen to my full story at KJZZ’s Arizona Science Desk:
Seventy-plus years into the Atomic Age, the United States still lacks a good radiation-dosage test.
But the ASU Radiation Biodosimetry Test (ARad), a device being developed by Arizona State University’s Biodesign Institute, could soon help doctors triage victims of a nuclear attack by gauging their exposure to ionizing radiation via changes in gene expression.
ARad is one of only a few tests under development that can detect radiation exposure levels. Read/listen to my full story at KJZZ’s Arizona Science Desk:
