Category Archives: Biochemistry

Study Sequences Record Amount of Human microRNA

Discovered  in the nematode c. elegans, miRNA were once thought to be leftovers of an era when RNA ruled life processes on Earth (image by Bob Goldstein, UNC Chapel Hill).

An Arizona State University team has used a unique high-throughput screening system to complete the largest-ever analysis of microRNAs (miRNA), the puzzling little cousins of RNA that help regulate gene expression.

Their findings offer a new explanation for why groups of similar miRNA sequences, called miRNA families, are so plentiful in higher species of animals, including humans.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
ASU Completes Largest-Ever microRNA Study

Brain Activity Patterns Set Young Runners Apart from Healthy Peers

Spatial maps for (from top) the default mode network, frontoparietal network and motor network  (image courtesy Gene Alexander of University of Arizona).

The book The Runner’s Brain told runners how their minds could change their running. Now a University of Arizona study says the reverse might be true as well.

Using functional connectivity MRI (fcMRI), they found significant differences in areas that are active when the brain is at rest. Possibly, such networks could play a key role in the effects of aging and neurodegenerative diseases.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
Arizona Study: Brains Of Young Adult Runners Differ From Those Of Healthy Peers

As in Chile, So on Mars: Silica Nodules and the Case for Micobial Life

Geysers at El Tatio, in Chile. Photo by Chmouel Boudjnah.

Work in the Chilean desert by Arizona State University scientists has reopened debate regarding the biological origins of Martian silica fragments found in 2007 — and strengthened the case for life on Mars billions of years ago.

NASA’s Spirit rover churned up the opaline silica deposits as it explored the Columbia Hills area of Mars’s Gusev Crater.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
Silica Nodules In Chile Argue For Ancient Life On Mars

Jeopardy-Winning Computer Crunches Numbers to Fight ALS

Watson on Jeopardy stage set at the Computer History Museum in Mountain View, California. Photo by Atomic Taco.

Barrow Neurological Institute is working with IBM’s Jeopardy-winning supercomputer, Watson, to identify treatment targets for Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis, or ALS.

ALS is a poorly understood neuromuscular disease with only limited treatment options. Its capacity to strike anyone, at any time, seemingly without pattern, has puzzled researchers.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
BM’s Watson Computer Helps Barrow Identify New ALS Genes

TGen Brain Cancer Study Links Complexity to Treatability

TGen Headquarters. Photo by BenjaMurph.

New findings by the Translational Genomics Research Institute, or TGen, point to a surprising pattern in the brain cancer glioblastoma multiforme (GBM), the most common and deadly type of gliomas.

GBMs are aggressive, invasive and so genetically and structurally complex that advanced, targeted therapies have struggled to find vulnerabilities to attack.

Read/listen to my full story at KJZZ’s Arizona Science Desk:
TGen Brain Cancer Study Finds Surprising Benefit In Tumor Complexity